The NukEx Mag Extreme SC and NukEx Mag Extreme SL Kits are designed for rapid manual and automated extraction of nucleic acids from a wide range of difficult samples (e.g. human samples, veterinary samples, insects, food samples, etc.). The kits are designed for use with tissue homogenizers for mechanical disruption of samples and subsequent purification of nucleic acids using magnetic beads. The purified nucleic acids can be used directly as template for real time (Reverse Transcription-) PCR or any kind of enzymatic reactions. NukEx Mag Extreme Kits allow easy automation on common liquid handling instruments or automated magnetic separators.